Burkholderia infections are prevalent all over the world, including regions such as the APAC. Burkholderia infection is a Gram-negative bacterium that causes infections from humans to other animals and even in the soil. It is easily transmitted through any type of open wounds, such as cuts, burns, or open sores. Burkholderia infections can also infect humans via infected respiratory secretions, vaginal secretions, or other blood products. Many infections are relatively mild and only go away on their own after a few weeks, but some can become quite serious, causing death if not treated properly.
Since the name itself describes its shape, it is often referred to as pseudomallei. This is because the stalk of the bacterium looks like a pear or pseudomallei shape, with the titer plate (red arrow) being situated in the middle of this. The staphylococcus bacteria that causes the infection is the same one responsible for food poisoning. Although many types of MRSA have been identified, only Burkholderia cell is the primary cause of severe infections, especially sepsis (severe infection), in which people can die very quickly if not treated promptly.
In regions such as Singapore, there has been an increasing prevalence of Burkholderia infections. For instance, according to the National Institutes of Health (NIH), serological surveys have depicted that the prevalence rate of burkholderia infections in Singapore is around 0.2%.
In the laboratory, Burkholderia infections have been found to grow in three different environments, which are an environment with multiple organisms (such as a hospital), an anaerobic environment without any oxygen, and a warm moist environment. It was also found that the only way to get rid of burkholderia infections was by using antibiotics, although there is the possibility of resistance to antibiotics in the future. The organism is now only known to grow in the eye, liver, kidney, and bladder, with no further spread known. Because of the potential for antibiotic resistance, Burkholderia infections are one of the most difficult antimicrobial viruses to treat in the field. This makes it particularly important for healthcare workers who may come into contact with infected patients and thus become susceptible to serious Burkholderia infections.
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